In the Universal Century, specifically 0096, the aftermath of war has left fragile peace, prompting uncertainty. A sixteen-year-old student named Banagher Links travels to the Industrial 7 space colony on a school trip. Unfortunately, his plans are thwarted due to a broken shuttle, and he becomes stranded. Banagher's reality is shaken when he encounters Audrey Burne, a girl frantically seeking the Vist Foundation leader, Cardeas Vist. Audrey wants Cardeas to abstain from utilizing the destructive "Laplace's Box." Banagher's conviction is tested as warring factions, like Neo Zeon and the Earth Federation Forces, engage in a cosmic struggle for dominance. Cardeas lends Banagher the key to the box - a mobile suit dubbed "The Unicorn Gundam." In the Mobile Suit Gundam Unicorn RE:0096, events spin out of control, and destiny hangs in the balance.