Despite being just 19, Minato Sahashi is a gifted individual facing struggles. Having failed his college entrance exams twice, his peers consider him a failure. However, his life takes an unexpected turn when he meets an otherworldly, stunning woman who falls from the sky. This woman is a Sekirei- possessing extraordinary abilities, she seeks humans with the Ashikabi gene by kissing them, unlocking their hidden potential. Seeing potential in Minato, Musubi chooses to partner with him, binding them in the Sekirei world. Their partnership sees them entering the "Sekirei Plan" where they face fierce competition from others for survival. However, none of the contestants are aware of the dangers that lurk within the competition, and the stakes are much higher than they had anticipated.