Youkai Academy is not your typical boarding school. It's a place where monsters are taught to coexist with humans. Students attend the academy in human form and take regular academic classes like literature, gym, foreign language, and mathematics. However, there is one strict rule that everyone must follow. Humans found on school premises are to be executed immediately! Tsukune Aono is an ordinary teenager who can't seem to get into any high school due to his poor grades. His parents enroll him in Youkai Academy as a last resort to ensure his education. As Tsukune enters this new world, he meets the most beautiful girl on campus, Moka Akashiya. Little does he know that Moka is a vampire and a monster that he's not supposed to associate with. Despite the danger, Tsukune decides to stay in this perilous realm to continue his relationship with Moka. However, he soon learns that not all creatures are friendly. Rosario to Vampire is a supernatural school comedy that follows Tsukune's romantic experiences, misadventures, and encounters with a plethora of stunning but dangerous creatures.