The plot centers around Cadis Etrama di Raizel who, after being in slumber for 820 years, embarks on a fresh start as a high school pupil. However, his serene existence is short-lived as he encounters a gang of assailants, the "Unions." The anime tracks Raizel and his devoted aide, Frankenstein, as they tirelessly safeguard his newfound human comrades from unexplained dangers.