Flying ninjas from the Land of Sky have launched a devastating surprise attack on their old foe, Konohagakure, seeking revenge. Naruto Uzumaki is keen to join the fight, but he's delayed by a mysterious doctor named Shinnou who needs his help to save an injured person. While delivering the wounded man to the hospital, Naruto meets Amaru, a troubled youngster from a nearby village seeking Shinnou's aid. Meanwhile, the invaders withdraw to regroup, giving Tsunade a chance to dispatch Sai, Shikamaru Nara, and Kakashi Hatake to strike their base. At the same time, she sends Naruto, Sakura Haruno, and Hinata Hyuuga on a mission with Shinnou and Amaru. But Orochimaru has his own schemes, ordering Sasuke Uchiha to capture the doctor skilled in reincarnation techniques. As the escort group uncovers the sinister truth behind the attacks, sinister plans are set in motion. But even when reunited with an unexpected figure, Naruto remains unwavering in his mission to end the warfare before it causes any more damage.