"Vocal medicine" has emerged as a reputable discipline that rivals traditional medical practices. Its focus is on treating health ailments and injuries through the use of songs. Aspiring healers from all over the world work towards mastery of this art to help others harness the power of their voices. One such talent is Kana Fujii, a gifted singer who found her calling after a life-changing experience. Kana, along with her ambitious colleague Reimi Itsushiro and easygoing friend Hibiki Morishima, trains under the guidance of Ria Karasuma at Karasuma Phoniatric Clinic. While pursuing their goals, Kana and her companions encounter a wide range of eccentric healers, discovering that vocal medicine entails more than just rigorous study.