In Terra, inexplicable natural disasters have been striking various regions without warning. To avoid these calamities, most individuals have migrated to mobile cities crafted over time. The aftermath of these catastrophes has resulted in the emergence of Originium, an energy source that has fuelled rapid technological advancements. However, it has also unfortunately unleashed an unrelenting illness known as Oripathy. As those afflicted with Oripathy gradually turn to crystals and become infectious after they pass away, many nations enforce discriminatory policies of segregation and forced labor against those who have contracted the disease. As a result, numerous oppressed citizens are beginning to revolt. Rhodes Island, a pharmaceutical corporation working tirelessly to find a cure for Oripathy, takes up arms to launch a mission aimed at saving everyone from this plaguing illness.