Located in Japan, Academy City stands as a leader in scientific advancement, with a technological prowess that outpaces the rest of the world by 30 years. The city's unique demographics are dominated by students, over three-fourths of whom are espers, honing their psychic abilities in various institutions. Touma Kamijou belongs to this group of students, possessing the lowest psychic rank of zero, but with a power that eludes the grasp of even the most astute scientists: "Imagine Breaker," which grants him the ability to nullify other supernatural abilities. Despite his unique gift, Kamijou navigates life as a normal high school student, until he meets Index Librorum Prohibitorum, a young girl with a dangerous secret. She has committed to memory all of the forbidden grimoires, making her a target for a hostile organization. In the face of danger, Kamijou rises to protect his new friend, embarking on an extraordinary journey through a realm of the supernatural.