Despite their continuous efforts to combat the Terraformars, genetically-modified humanoid cockroaches that emerged from insect experiments on Mars long ago, the Annex I group in Terra Formars Revenge have failed to find a cure for the Alien Engine Virus plaguing Earth. Compounded by the realization that other squads have nationalist aspirations, the war-torn team must endure even more danger. In a fight for national sovereignty, the team must defend themselves not only against the Terraformars but also against rival nations, all while striving for global domination.