In Japan, drugs have sparked a rising wave of crime, prompting the police to create a specialized unit, STAND, to tackle the issue. Rei Izumi, a rookie on the narcotics investigation team, is tasked with recruiting potential members for STAND. With a reputation for her strong sense of justice and dedication to her job, Rei also possesses a unique advantage — immunity to most types of drugs. However, as Rei sets out to find suitable candidates for STAND, she encounters unexpected challenges. Each potential member has their own ideologies, emotions, and reservations about joining the team to regulate drugs. Moreover, her credibility as a narcotics officer is also questioned by the diverse personalities she comes across, causing friction and unpredictability in her daily routine. As she navigates the perilous world of drug trafficking, filled with deceit and secrecy, Rei quickly learns that persuading potential STAND members is just the beginning of her troubles. Her own safety becomes a pressing issue, and the stakes become higher than she ever imagined.