Blade is faced with unraveling a string of perplexing abductions in Sin. Through exploring the unforgiving underbelly of the city, a convoluted enigma is revealed. At its core lies the SinTEK organization and its leader, a heartless and alluring woman named Elexis Sinclair, who is a brilliant biochemist with an unrelenting drive to accomplish her objective. That objective being a plan that could either propel human evolution to the next level or bring about humanity's downfall.