The Public Safety Bureau was rocked by a runaway vehicle driven by Izumi Yasaka, a counselor who had fled from Sanctuary, an isolation and rehabilitation center for latent criminals. Inspectors Mika Shimotsuki and Akane Tsunemori were on the case, but before they could question Izumi, they received a sudden order from Sanctuary to return her. Despite their compliance, Tsunemori vowed to continue investigating with the Bureau team and demanded that Izumi be escorted back personally. As the investigation into Sanctuary continued, Inspector Shimotsuki finally got her chance to lead an important case. Together with her Enforcer team, she uncovered the facility's secrets.