Accompanied by his faithful Pikachu, Satoshi embarks on a mission to become a "Pokémon Master," joined by Takeshi, a trainer who adores female Pokémon, and Kasumi, a robust trainer who holds an affection for Satoshi. The trio journeys across different regions, including Kanto, the Orange Islands, and Johto, battling tough competition at the Pokémon League. However, their progress is frequently impeded by the notorious Pokémon thieves known as Musashi, Kojirou, and Nyarth, who are part of the nefarious "Team Rocket." Despite the villains' numerous attempts to harm them, Satoshi and his loyal Pokémon successfully foil Team Rocket's scheming with their cleverness and expertise.