Humans populate a dark and brooding world, pitted against one another in a struggle for power against the ruling Darkstalkers. Zombies, vampires, and werewolves all vie for supremacy, driven by their own personal desires. However, their struggles become insignificant when the Huitzil, a race of Aztec robots, declare humanity unworthy of salvation, unleashing war upon the world. Meanwhile, a solar god from beyond the stars envisions Earth as his latest conquest. In this dire situation, the Darkstalkers must reluctantly unite to defend their world from destruction.