Following his removal from the Lupin case, Inspector Zenigata feels disheartened and drinks with Lupin and Jigen. Lupin suggests that they team up with Zenigata to investigate Shot Shell, a group of arms dealers. Lupin enlists his partners - Jigen, Goemon, and Fujiko - and works with Zenigata to steal a Russian submarine to aid in their mission. They also abduct a scientist, Karen Korinsky, to operate the sub and keep her safe from Shot Shell. Meanwhile, the ICPO assigns Keith Hayden to the case, who wants Lupin and his gang dead. Keith follows them wherever they go, targeting each of them.