After losing their first baseball game, the Little Busters decide to lift their spirits with a pancake party. It's been a semester since Kyousuke Natsume's return and Riki Naoe continues to support the team, helping old and new members confront their inner struggles. However, strange events unfold, leading Rin and Riki to uncover the truth behind the "secret of this world." Unbeknownst to them, their discovery will shatter the peaceful lives of the Little Busters forever. Little Busters!: Refrain brings a poignant end to the ensemble's stories, exploring themes of regret, friendship, and vulnerability.