Since the Teppelin battle, seven years have passed and humanity has successfully reclaimed the earth's surface. This has led to a time of unparalleled peace and prosperity. Unfortunately, the population growth has given rise to an unknown and dominant enemy known as the Anti-Spiral. This ruthless and manipulative adversary has left humans feeling helpless against them. However, Team Dai-Gurren reunites to take a stand and fight back against this formidable foe, even when hope appears to be lost.