Although Tsukushi Makino comes from a poor family, she simply wants to finish her final two years at Eitoku Gakuen without causing any disruptions. Unfortunately, her defense of a friend against the F4's wrath - a group of wealthy and powerful male students - leads to her receiving the dreaded red card, a symbol of the F4's "Declaration of War" and her sudden notoriety. However, Tsukushi refuses to give up and even begins to develop romantic feelings for one of the F4 members, Hanazawa Rui. As she navigates through her complicated feelings, Tsukushi discovers hidden depths in herself and the F4.