On the day her family relocated to their new residence, a five-year-old called Ami-chan befriended three animals who conversed with her. These creatures emerged from a bedroom floor's door, which she discovered led to Animal Yokocho - another realm. Among the trio were Issa, an extremely candid and softly spoken panda, Kenta, a highly strung bear fond of red scarfs who often mimicked a rough exterior, and Iyo, a rabbit who prioritized her own pleasure and wellbeing over that of her companions' happiness (and safety). Although she is just five, Ami-chan is the best-thought-out member of the gang, and though she is initially cautious, she gradually warms to them and begins to socialize with them during her free hours. They engage in various activities to pass the time during a standard day, often playing innocuous games with a twist intrinsic to AniYoko's style. Unfortunately for Ami-chan, the AniYoko version frequently ends up being strikingly different, much less reasonable, and usually more perilous than the regular edition.